Ayurveda

What are the General Symptoms of Alagille Syndrome?

Alagille syndrome results due to decreased number of bile ducts in the liver. As a result of it the bile gets deposited in the liver itself. This leads to the damage of the liver.


General Symptoms of the Alagille syndrome

The symptoms of the Alagille syndrome varies even among the members belonging to the same family. In the Alagille syndrome primarily the liver gets damaged. The following are the associated symptoms of the Alagille syndrome that take place due the damage of the liver.

Jaundice:

Due to the rise in the Bilirubin content in the blood jaundice occurs. This causes yellowing of the skin and whites on the eye. High Bilirubin content in the urine darkens the urine, stools become pale white or grey from lacking of Bilirubin in the intestine. The jaundice that occurs due to Alagille syndrome persists unlike the Jaundice that occurs in new born children.

Pruritus:

The accumulation of Bilirubin in the blood causes itching. This is called Pruritus. It Starts around third month of aging and may be severe.

Malabsorption and growth problems:

In the absence of bile fats, fat soluble vitamins are not properly absorbed. Due to this malabsorption occurs. This results in Diarrhoea. This affects growth in children and even delays puberty. Other symptoms of malabsorption include fractures, eye problems, blood-clotting problems, and learning delays.

Xanthomas:

These are formed due to abnormally high cholesterol in the blood. This results in yellow bumps in the skin. Other organs that are affected include abdomen, knees, elbows, hands, and around the eyes and are harmless.

Leave a reply

Your email address will not be published. Required fields are marked *