is an inherited disorder. Manifestations of the disease are mostly congenital in nature. It is characterised by scarring and appearance of cystic lesions on the liver. It is a serious liver condition.
The liver is a very important organ as far as the metabolic activities of the body are concerned. It is responsible for disposing off toxins from the body, bile production for metabolism of food, especially fats and sugars, converting and storing energy for future use. Liver diseases figure in the list of top 10 killer diseases in the United States. One out of 10 Americans is affected by some form of liver disease. This particular liver condition is estimated to affect around 1 in 20,000 babies born. It is a disease which is very often manifested in infancy. However, it is known to affect adults too.
Causes of Hepatic Fibrosis
- Any condition which seriously affects the functioning of the liver is responsible for the disease.
- Acute or chronic liver injury.
- Diseases like hepatitis, progressive cirrhosis, portal hypertension, liver cancers etc are responsible for the said condition.
- It also results from a congenital defect where the ductal plate is malformed in a fetus. The ductal plate is a cylindrical shaped layer of cells that sorrounds the portal vein which is the main vein that leads to the liver from the gastrointestinal tract.
Symptoms of the condition
The different symptoms of the condition are as follows:
- Jaundice or yellowing of skin.
- Hepatomegaly or enlargement of liver.
- Lump or formation of malignant mass in the liver or bile ducts.
- Altered bowel habit.
- Chest pain.
- Enlargement of spleen.
- Development of varices or dilation in blood vessels of the stomach.
- Abdominal pain.
- Polycystic kidney disease impairing renal function.
- Portal hypertension or increased pressure in the portal vein caused by blockages.
Treatment of Hepatic Fibrosis
It is important to treat and manage the underlying liver disorder in order to treat the condition.